At least 50 children are thought to be among the dead.
The attack by the Syrian government was on the rebel enclave of eastern Ghouta.
The suburbs are near Damascus and host rebel groups.
Concerns are growing that Syria faces the worst humanitarian catastrophe of its seven-year civil war after more than 250 civilians were reportedly killed in airstrikes by forces loyal to Bashar al-Assad within two days.
Amnesty International said there were “flagrant war crimes” going on in eastern Ghouta, near the capital Damascus.
U.S. forces killed scores of Russian mercenaries in Syria last week in what may be the deadliest clash between citizens of the former foes since the Cold War, according to one U.S. official and three Russians familiar with the matter.
More than 200 contract soldiers, mostly Russians fighting on behalf of Syrian leader Bashar al-Assad, died in a failed attack on a base held by U.S. and mainly Kurdish forces in the oil-rich Deir Ezzor region, two of the Russians said. The U.S. official put the death toll at about 100, with 200 to 300 injured.
The Russian assault may have been a rogue operation, underscoring the complexity of a conflict that started as a domestic crackdown only to morph into a proxy war involving Islamic extremists, stateless Kurds and regional powers Iran, Turkey and now Israel. Russia’s military said it had nothing to do with the attack and the U.S. accepted the claim. Defense Secretary Jim Mattis called the whole thing “perplexing,” but provided no further details.
But several Afghan officials have confirmed the plans, on the record.
China has formally denied reports that it is building a military base on the Afghanistan-Tajikistan border for the Afghan armed forces. But Afghan security officials have confirmed the original report, and offered additional details of the secretive Chinese presence in the region.
In January, reports emerged that Beijing and Kabul had come to an agreement for China to build and supply a military base in Badakhshan, the remote panhandle of Afghanistan that borders China and Tajikistan.
But at a January 25 press briefing, Chinese Defense Ministry spokesman Wu Qian denied those claims. “The so-called issue that China is building a military base in Afghanistan is groundless,” he said.
An Israeli F-16 fighter jet has crashed amid Syrian anti-aircraft fire after an offensive against Iranian targets in Syria, the Israeli military says.
The two pilots parachuted to safety before the crash in northern Israel. It is believed to be the first time Israel has lost a jet in the Syrian conflict.
Israel was carrying out strikes after the launch of an Iranian drone into Israel. The drone was intercepted.
Syria accused Israel of “aggression”, as Israel then launched more strikes.
Israel Defense Forces (IDF) tweeted: “Moments ago, IAF aircraft, targeted the Syrian Aerial Defense System & Iranian targets in Syria. 12 targets, including 3 aerial defense batteries & 4 Iranian military targets, were attacked. Anti-aircraft missiles were fired towards Israel, triggering alarms in northern Israel.”
Israeli strikes in Syria are not unusual, the BBC’s Middle East correspondent Tom Bateman says, but the loss of an Israeli fighter jet marks a serious escalation.
The US led an attack that killed more than 100 pro-Assad regime soldiers in Syria on Thursday.
The attack was a response to a pro-Assad airstrike on the headquarters of a long-time US ally in Syria.
The US has been edging closer and closer to fighting the Syrian government and Russia since the fall of ISIS.
A US attack on forces loyal to Syrian President Bashar Assad killed more than 100 in the country’s north on Thursday, and the regime came roaring back with airstrikes of its own on rebel forces near Damascus.
The airstrikes from Assad killed 21 and injured 125, the Syrian Observatory for Human Rights reported on Thursday.